Main goals of the BrainTrain project To find therapeutic strategies for diseased brain and training young researchers with an excellent integrative and multidisciplinary perspective on brain research are the main objectives of the project: 1. Applying novel gene mapping strategies to identify new disease loci. This effort will build on our novel models for inheritance [...]
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Training: students can apply for the oncoming courses and workshops >Read more
Video
JoVE video paper
JoVE, the Journal of Visualized Experiments gives the opportunity to share a method with the science community by actually showing how to prepare and perform an experiment. We used the opportunity to create a video-methods paper of the well-established calcium imaging technique in immature brain slices.
The increasing prevalence for neurodegenerative disease in our aging population poses a growing problem for healthcare.
Many brain disorders are to be considered 'synaptic diseases" or 'synaptopathies' and cellular function of synapses.
The synapse is a specialized structure between two neurons at which basal neuronal communication takes place.
In neuropsychiatric disorders associated with reduced cognitive abilities, such as age-related cognitive decline, but also mental retardation, the ability of synapses to alter their strength is strongly affected.
The etiology of many disorders including age-related cognitive decline and neurodegenerative disorders such as dementia and Parkinson’s disease is still poorly understood.